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Auricular Acupuncture J Clin Oncol. 2003 Nov 15;21(22):4120-6. |
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November 1, 2003 |
Author / Title |
Analgesic effect of auricular acupuncture for cancer pain: a randomized, blinded, controlled trial. / Alimi D, Rubino C, Pichard-Leandri E, Fermand-Brule S, Dubreuil-Lemaire ML, Hill C. |
Abstract |
PURPOSE: During the last 30 years, auricular acupuncture has been used as complementary treatment of cancer pain when analgesic drugs do not suffice. The purpose of this study is to examine the efficacy of auricular acupuncture in decreasing pain intensity in cancer patients. PATIENTS AND METHODS: Ninety patients were randomly divided in three groups; one group received two courses of auricular acupuncture at points where an electrodermal signal had been detected, and two placebo groups received auricular acupuncture at points with no electrodermal signal (placebo points) and one with auricular seeds fixed at placebo points. Patients had to be in pain, attaining a visual analog score (VAS) of 30 mm or more after having received analgesic treatment adapted to both intensity and type of pain, for at least 1 month of therapy. Treatment efficacy was based on the absolute decrease in pain intensity measured 2 months after randomization using the VAS. RESULTS: The main outcome was pain assessed at 2 months, with the assessment at 1 month carried over to 2 months for the eight patients who interrupted treatment after 1 month. For three patients, no data were available because they withdrew from the study during the first month. Pain intensity decreased by 36% at 2 months from baseline in the group receiving acupuncture; there was little change for patients receiving placebo (2%). The difference between groups was statistically significant (P <.0001). CONCLUSION: The observed reduction in pain intensity measured on the VAS represents a clear benefit from auricular acupuncture for these cancer patients who are in pain, despite stable analgesic treatment. |
Conclusion |
The observed reduction in pain intensity measured on the VAS represents a clear benefit from auricular acupuncture for these cancer patients who are in pain, despite stable analgesic treatment. |
Local |
Pain Management Unit, INSERM, U521, Villejuif, France. |
Web |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14615440&query_hl=7 |
xo |
Auricular Acupuncture Am J Chin Med. 2003;31(2):285-94. |
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Author / Title |
Establishing the existence of the active stomach point in the auricle utilizing radial artery tonometry. / Ikezono E, Ikezono T, Ackerman J. |
Abstract |
One component of Oriental medicine diagnosis utilizes the palpation of the radial pulse both for internal medicine and also to help clinicians accurately choose body acupuncture treatment points. In the mid-1980s, an attempt was made to capture diagnostic information with three pressure transducers positioned bilaterally over the radial arteries in such a fashion as to simulate classical Chinese pulse diagnosis (Yoon and Ikezono, 1986 and 1987). The results of this pilot study were subsequently difficult to replicate. In the early 1950s, Paul Nogier in Lyon, France introduced a different pulse diagnostic technique (Nogier, 1976). By touching an acupuncture needle on an active auricular acupuncture point, the radial artery wall over the styloid process changes in tone more prominently than when inactive points on the acuricle are touched. This dermal/cardiovascular reflex of pulse diagnostic technique helps, then to localize salient auricular points to treat regarding a patient's illness. Objective digitalized measurements of the Nogier radial arterial pulse wave were performed by computerized tonometry. This demonstrated that when an active stomach point in the auricle (n = 11) was detected utilizing an imperceptible electric current, the initial upstroke of the pressure wave, the pulse pressure and the peak-to-peak interval of the radial artery pulse wave all increased significantly compared to placebo point electronic detection. Thus, the existence of an active auricular point on the auricle was verified by radial artery tonometry. |
Conclusion |
Thus, the existence of an active auricular point on the auricle was verified by radial artery tonometry. |
Local |
New Obesity Research, 3-7-3, Shimizu, Suginamiku, Tokyo 167-0033, Japan. |
Web |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12856867&query_hl=28 |
xo |
Auricular Acupuncture Am J Physiol Regul Integr Comp Physiol. 2004 Oct;287(4):R852-62. Epub 2004 Jun 24. |
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Author / Title |
Medullary substrate and differential cardiovascular responses during stimulation of specific acupoints. / Tjen-A-Looi SC, Li P, Longhurst JC. |
Abstract |
Electroacupuncture (EA) at P5-P6 acupoints overlying the median nerve reduces premotor sympathetic cardiovascular neuronal activity in the rostral ventral lateral medulla (rVLM) and visceral reflex pressor responses. In previous studies, we have noted different durations of influence of EA comparing P5-P6 and S36-S37 acupoints, suggesting that point specificity may exist. The purpose of this study was to evaluate the influence of stimulating P5-P6 (overlying the median nerve), LI4-L7 (overlying branches of the median nerve and the superficial radial nerve), LI6-LI7 (overlying the superficial radial nerve), LI10-LI11 (overlying the deep radial nerves), S36-S37 (overlying the deep peroneal nerves), or K1-B67 (overlying terminal branches of the tibial nerves) specific acupoints, overlying deep and superficial somatic nerves, on the excitatory cardiovascular reflex and rVLM responses evoked by stimulation of chemosensitive receptors in the cat's gallbladder with bradykinin (BK) or direct splanchnic nerve (SN) stimulation. We observed point-specific differences in magnitude and duration of EA inhibition between P5-P6 or LI10-LI11 and LI4-L7 or S36-S37 in responses to 30-min stimulation with low-frequency, low-current EA. EA at LI6-LI7 and K1-B67 acupoints as well as direct stimulation of the superficial radial nerve did not cause any cardiovascular or rVLM neuronal effects. Cardiovascular neurons in the rVLM, a subset of which were classified as premotor sympathetic cells, responded to brief (30 s) stimulation of the SN as well as acupoints P5-P6, LI10-LI11, LI4-L7, S36-S37, LI6-LI7, or K1-B67, or underlying somatic pathways in a fashion similar to the reflex responses. In fact, we observed a significant linear relationship (r(2) = 0.71) between the evoked rVLM response and reflex change in mean arterial blood pressure. In addition, EA stimulation at P5-P6 and LI4-L7 decreased rVLM neuronal activity by 41 and 12%, respectively, for >1 h, demonstrating that prolonged input into the medulla during stimulation of somatic nerves, depending on the degree of convergence, leads to more or less inhibition of activity of these cardiovascular neurons. Thus EA at acupoints overlying deep and superficial somatic nerves leads to point-specific effects on cardiovascular reflex responses. In a similar manner, sympathetic cardiovascular rVLM neurons that respond to both visceral (reflex) and somatic (EA) nerve stimulation manifest graded responses during stimulation of specific acupoints, suggesting that this medullary region plays a role in site-specific inhibition of cardiovascular reflex responses by acupuncture. |
Conclusion |
Thus EA at acupoints overlying deep and superficial somatic nerves leads to point-specific effects on cardiovascular reflex responses. In a similar manner, sympathetic cardiovascular rVLM neurons that respond to both visceral (reflex) and somatic (EA) nerve stimulation manifest graded responses during stimulation of specific acupoints, suggesting that this medullary region plays a role in site-specific inhibition of cardiovascular reflex responses by acupuncture. |
Local |
Medical Science 1 C240, College of Medicine, Univ. of California, Irvine, California 92697-4075, USA. |
Web |
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Auricular Acupuncture Neurol Res. 2004 Oct;26(7):797-800. |
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Author / Title |
Objectivation of cerebral effects with a new continuous electrical auricular stimulation technique for pain management. / Szeles JC, Litscher G. |
Abstract |
AIMS: The electrical point stimulation system (P-STIM) reflects a new, miniaturized system for pain therapy through ear acupuncture. For this reason, ultrathin needles were applied at the ear. The needles stimulate the acupuncture areas at the ear using electrical impulses, which come from a little generator applied behind the acupunctured ear. METHODS: This study describes continuous, non-invasive measurements of near infrared spectroscopy (NIRS) and multidirectional transcranial Doppler sonography in two healthy females (aged 23 and 27 years) during stimulation with P-STIM, for the first time. RESULTS: The results of the pilot measurements have shown that electrical point stimulation using the new electrical stimulation system on eye acupuncture points is able to modulate the mean blood flow velocity (vm) of the supratrochlear artery. These effects were present using a stimulation frequency of 100 Hz. A lower increase in vm was found in the middle cerebral artery. In addition, stimulus induced, quantifiable and reproducible alterations of the regional cerebral NIRS parameters were be detected. CONCLUSION: For the first time, P-Stim allows intermittent ear acupuncture stimulation for up to several days in combination with complete mobility for the patient. |
Conclusion |
The results of the pilot measurements have shown that electrical point stimulation using the new electrical stimulation system on eye acupuncture points is able to modulate the mean blood flow velocity (vm) of the supratrochlear artery. These effects were present using a stimulation frequency of 100 Hz. A lower increase in vm was found in the middle cerebral artery. In addition, stimulus induced, quantifiable and reproducible alterations of the regional cerebral NIRS parameters were be detected. CONCLUSION: For the first time, P-Stim allows intermittent ear acupuncture stimulation for up to several days in combination with complete mobility for the patient. |
Local |
Department of Vascular Surgery, Medical University of Vienna, Austria |
Web |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15494125&query_hl=28 |
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