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| Clinical Trial • BMJ. 2005 Aug 13;331(7513):376-82. Epub 2005 Jul 29. |
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August 1, 2005 |
| Author / Title |
Acupuncture in patients with tension-type headache: randomised controlled trial / Melchart D, Streng A, Hoppe A, Brinkhaus B, Witt C, Wagenpfeil S, Pfaffenrath V, Hammes M, Hummelsberger J, Irnich D, Weidenhammer W, Willich SN, Linde K. |
| Abstract |
OBJECTIVE: To investigate the effectiveness of acupuncture compared with minimal acupuncture and with no acupuncture in patients with tension-type headache. DESIGN: Three armed randomised controlled multicentre trial. SETTING: 28 outpatient centres in Germany. PARTICIPANTS: 270 patients (74% women, mean age 43 (SD 13) years) with episodic or chronic tension-type headache. INTERVENTIONS: Acupuncture, minimal acupuncture (superficial needling at non-acupuncture points), or waiting list control. Acupuncture and minimal acupuncture were administered by specialised physicians and consisted of 12 sessions per patient over eight weeks. MAIN OUTCOME MEASURE: Difference in numbers of days with headache between the four weeks before randomisation and weeks 9-12 after randomisation, as recorded by participants in headache diaries. RESULTS: The number of days with headache decreased by 7.2 (SD 6.5) days in the acupuncture group compared with 6.6 (SD 6.0) days in the minimal acupuncture group and 1.5 (SD 3.7) days in the waiting list group (difference: acupuncture v minimal acupuncture, 0.6 days, 95% confidence interval -1.5 to 2.6 days, P = 0.58; acupuncture v waiting list, 5.7 days, 3.9 to 7.5 days, P < 0.001). The proportion of responders (at least 50% reduction in days with headache) was 46% in the acupuncture group, 35% in the minimal acupuncture group, and 4% in the waiting list group. CONCLUSIONS: The acupuncture intervention investigated in this trial was more effective than no treatment but not significantly more effective than minimal acupuncture for the treatment of tension-type headache. TRIAL REGISTRATION NUMBER: ISRCTN9737659. |
| Conclusion |
The acupuncture intervention investigated in this trial was more effective than no treatment but not significantly more effective than minimal acupuncture for the treatment of tension-type headache. |
| Local |
Centre for Complementary Medicine Research, Department of Internal Medicine II, Technische Universitat Munchen, Kaiserstr 9, 80801 Munich, Germany. |
| Web |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16055451&query_hl=1 |
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| Clinical Trial • Acupunct Med. 2005 Jun;23(2):70-6. |
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June 1, 2005 |
| Author / Title |
The effectiveness of acupuncture for depression--a systematic review of randomised controlled trials. / Mukaino Y, Park J, White A, Ernst E. |
| Abstract |
OBJECTIVE: To summarise the existing evidence on acupuncture as a therapy for depression. METHODS: RCTs were included, in which either manual acupuncture or electroacupuncture was compared with any control procedure in subjects with depression. Data were extracted independently by two authors. The methodological quality was assessed. Pre and post means and SDs for depression specific measures were extracted, when available, for meta-analysis. RESULTS: Seven randomised comparative trials involving 509 patients were included. The evidence is inconsistent on whether manual acupuncture is superior to sham, and suggests that acupuncture was not superior to waiting list. Evidence suggests that the effect of electroacupuncture may not be significantly different from antidepressant medication, weighted mean difference -0.43(95% CI -5.61 to 4.76). There is inconclusive evidence on whether acupuncture has an additive effect when given as an adjunct to antidepressant drugs. CONCLUSION: The evidence from controlled trials is insufficient to conclude whether acupuncture is an effective treatment for depression, but justifies further trials of electroacupuncture. |
| Conclusion |
The evidence from controlled trials is insufficient to conclude whether acupuncture is an effective treatment for depression, but justifies further trials of electroacupuncture. |
| Local |
Department of Complementary Medicine, Peninsula Medical School, Exeter, UK |
| Web |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16025787&query_hl=1 |
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| Clinical Trial • Zhongguo Zhong Xi Yi Jie He Za Zhi. 2005 Jun;25(6):556-8. |
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June 1, 2005 |
| Author / Title |
An introduction of the international standard for reporting intervention in clinical trials of acupuncture / Liu JP. |
| Abstract |
In clinical trials on acupuncture, the description of experimental intervention and controlled treatment are not usually reported adequately, for example, the acupoints and needles used, manipulation applied, duration of treatment, and other ancillary interventions and so on. This would limit the replication of the trial findings and application of the effective therapy. In 2001, an international group of acupuncture researchers discussed the problems in design and reporting of acupuncture clinical trials, and developed a standard for reporting intervention of the controlled clinical trials, abbreviated as 'STRICTA' recommendation, which contains 6 items to describe the rational of treatment, needling details, treatment regimen, co-interventions, practitioner' s background, and control intervention. This essay intends to introduce the standard and take two internationally published randomized trials of acupuncture as examples to illustrate the details. |
| Conclusion |
In 2001, an international group of acupuncture researchers discussed the problems in design and reporting of acupuncture clinical trials, and developed a standard for reporting intervention of the controlled clinical trials, abbreviated as 'STRICTA' recommendation, which contains 6 items to describe the rational of treatment, needling details, treatment regimen, co-interventions, practitioner' s background, and control intervention. |
| Local |
National Research Center in Complementary and Alternative Medicine, Norway. |
| Web |
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16025975&query_hl=1 |
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